VirB9_Atu1       ------------------------------------------------------------
VirB9_Atu2       ------------------------------------------------------------
VirB9_Ret        ---------------------------------------------------------MDR
VirB9_Bhe        ------------------------------------------------------------
TrwF_Eco         ------------------------------------------------------------
TraO_Eco         ------------------------------------------------------------
VirB9_Bsu        ------------------------------------------------------------
VirB9_Bpe        ------------------------------------------------------------
ComB2_Hpy1       ------------------------------------------------------------
ComB2_Hpy2       ------------------------------------------------------------
Cag8_Hpy1        MGQAFFKKIVGCFCLGYLFLSSAIEAAALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS
CagJ99_Hpy2      MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS
TrbG_Atu         ------------------------------------------------------------
TrbG_Atu2        ------------------------------------------------------------
TrbG_Rsp         ------------------------------------------------------------
TrbG_RK2         ------------------------------------------------------------
TrbG_Eae         ------------------------------------------------------------
LvhB9_Lpn        ------------------------------------------------------------
TrbG_Rpr         ------------------------------------------------------------
VirB9_Rpr        ------------------------------------------------------------
                                                                             

VirB9_Atu1       ------------------------------------------MTKKAFLTLACLLFA---
VirB9_Atu2       ------------------------------------------MTRKALFILACLFAA---
VirB9_Ret        NNSLRKGEQPARQIKAYQSGRFGHHIIPDIRRYRFQRGRRRTMKKKELLTLACLLFA---
VirB9_Bhe        --------------------------------------MMRILKTLFLAFIAAISCY---
TrwF_Eco         ------------------------------------------MKKLAIVALLASLH----
TraO_Eco         ------------------------------------------MKKLLLSAVVLSVLGGA-
VirB9_Bsu        ------------------------------------------MKRFLLACILITLA----
VirB9_Bpe        -----------------------------------------MMAARMMAAGLAATA----
ComB2_Hpy1       ------------------------MRKVLYALMGFLLVFSALKADDFLEEANETAPANL-
ComB2_Hpy2       ------------------------MRKVLYALMGFLLAFSALKADDFLEEANETAPANL-
Cag8_Hpy1        LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR
CagJ99_Hpy2      LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR
TrbG_Atu         ------------------------------------MNIQLRRFSATLTAATIVAVIVPF
TrbG_Atu2        ------------------------------------MNIRHRRQRATLAIGLLVFAIVPL
TrbG_Rsp         ----------------------------------------MHRTGLIAAAGCLATLVF--
TrbG_RK2         --------------------------------------MKKELFALVLAASVSVPAFA-A
TrbG_Eae         -------------------------------MNSRSSTMKKTLSALIVGAAVAVPSLALA
LvhB9_Lpn        ------------------------------------------MKKILLSAAVLLLS----
TrbG_Rpr         ------------------------------------------MKQLIIFCTFIILT----
VirB9_Rpr        -----------------------------MTIVRFYFLVFLLLSGFTVQRACPVVDDFN-
                                                                             

VirB9_Atu1       -------------AIGARAEDTPTAGRLD-------------------------------
VirB9_Atu2       -------------ATGAEAEDTPMAGKLD-------------------------------
VirB9_Ret        -------------ATGVMAEETPTPGRLD-------------------------------
VirB9_Bhe        -------------TTPSFAETAPVSARKD-------------------------------
TrwF_Eco         -------------AVPALALDVPSSSRYD-------------------------------
TraO_Eco         -------------ATNVMALEVGRNSPYD-------------------------------
VirB9_Bsu        --------------SPSWATKIPSGSKYD-------------------------------
VirB9_Bpe        --------------LSAHAFRIPTPGEQD-------------------------------
ComB2_Hpy1       -------------NHPMQDLNAIQGSFFDK------------------------------
ComB2_Hpy2       -------------NHPMQDLNAIQGSFFDK------------------------------
Cag8_Hpy1        D-------YQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEER
CagJ99_Hpy2      D-------YQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEER
TrbG_Atu         S----ASLSSRALAADGVTANEAKGMGISGQWRGSRG-----------------------
TrbG_Atu2        T----VLDPRTALAADGVTANEAKGMGLSTQWRGSKG-----------------------
TrbG_Rsp         -------AS--AAEAQSMTTNEVKGTSISRKWRGTAG-----------------------
TrbG_RK2         DPGADLTDLYFSGKNPELTAQERAAIAIAKKWEAGTA-----------------------
TrbG_Eae         APGDDIADKYFNKTNPTLTAQERAALAIAKRWEAGSAT----------------------
LvhB9_Lpn        --------------LGTYAQNNPTSLPTD-------------------------------
TrbG_Rpr         --------------LDIFALTMSRPLGRD-------------------------------
VirB9_Rpr        --------------SSRNNYVDDLPLTKD-------------------------------
                                                                             

VirB9_Atu1       -------PRMRYLAYNP------------------DQVVRLSTAVGATLVVTFGANETVT
VirB9_Atu2       -------PRMRYLAYNP------------------DQVVRLSTAVGATLVVTFATNETVT
VirB9_Ret        -------PRMRYLAYNP------------------DQVVHLSTAVGATLVVSFAANETVT
VirB9_Bhe        -------NRIRFVNYDP------------------YNVTKIIGSIRSSVQLEFADDEEVT
TrwF_Eco         -------HRIRYVTYNP------------------ADVVQVDTVLGVATHIMLEEGEQYL
TraO_Eco         -------YRIKSVVYNP------------------VNVVKIDAVAGVATHIVVAPDETYI
VirB9_Bsu        -------SRIQYVDYNS------------------GDVVLVRALPGVGARIVFAPGENIE
VirB9_Bpe        -------ARIQTVPYHP------------------EEVVLVRAWNGYVTRIVFDEQEKII
ComB2_Hpy1       --NRSKMSNTLNIDYFQ------------------GQTYKIRLRYAMATLLFFSKPISDF
ComB2_Hpy2       --NRSKMSNTLNIDYFQ------------------GQTYKIRLRYAMATLLFFSKPISDF
Cag8_Hpy1        AKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIE
CagJ99_Hpy2      AKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIE
TrbG_Atu         ---LVTKGPDGKVIFLYG-----------------EVQPSVVCSPLQVCDIELQGGEVVR
TrbG_Atu2        ---LVTKGADGKVIFLYG-----------------EVQPSVVCSPLQVCDIELQGGEVVR
TrbG_Rsp         ---LVTTGPDGKVIFLFG-----------------ETQPSVVCSPLQVCDIELQGGEIVR
TrbG_RK2         -GMRPVAGPGGSVRFLFG-----------------AQQPSIVCAVLQVCDVALQPGEQVN
TrbG_Eae         -GIKPVAGSGGAIKFVYG-----------------AQQPSIVCAVLQVCDVALQPGEQVN
LvhB9_Lpn        -------IRIKKVVYRE------------------NDVIPVHGIPFTTTQIQFAKQERVL
TrbG_Rpr         -------PRLRVMIYNP------------------DDVFKFTGYYGYQASIELAQEEEIV
VirB9_Rpr        -------NRIKTYIYNP------------------NEVYLLVLHFGFQSHIEFAKNEEIQ
                                                         .                   

VirB9_Atu1       AVAVSNSKDLAALPRGNYLFFKASK-----------VLPPQPVVVLTASDAGMRR-YVFS
VirB9_Atu2       SVAVSNSKDLAALPRGNYLFFKASQ-----------VLTPQPVIVLTASDSGMRR-YVFS
VirB9_Ret        AVAVSNSKTLAALPRGNYLFFKASQ-----------VLPPEPVVVLTASDAGMRR-YVFS
VirB9_Bhe        YVGIGNSVAWQVAPAGHFVFLKPRE-----------VQPVTNLQIVTSRQDGTKRSYQFE
TrwF_Eco         THAFGIPKPMPLPGRAGIFLSSRT----------------AELANTNLIVVTDRRSYKFR
TraO_Eco         THAFGDSESRTFAHKMNHFFVKPK----------------QAMSDTNLVIVTDKRTYNIV
VirB9_Bsu        DVASGFTQGWEFKASHNILYLKARSMTLSHSNQSIDMAPEPGKWDTNLMVTTDQRMYDFD
VirB9_Bpe        DVAAGFADGWQFSPEGNVLYIKAKSFPAQGSP---AQAPEPGLWNTNLLVKTDRRLYDFD
ComB2_Hpy1       VLGDKVGFDAKILESNDRILLIKP--------------LQIGVDSNISVIDSEGKIFSFY
ComB2_Hpy2       VLGDKVGFDAKILESNDRILLIKP--------------LQIGVDSNISVIDSEGKIFSFY
Cag8_Hpy1        ELNKKQAEETIKQRAKDKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFI
CagJ99_Hpy2      ELNKKQAEEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFI
TrbG_Atu         DVLVGDTVRWKVEPATSGAAGGQAIH--------LIVKPSEPNLVTSMVVTTSRRTYHIQ
TrbG_Atu2        DVLVGDTVRWKVEPRHRALAGGQAIH--------LIVKPSEPGLVTSMVVTTSRRTYHIQ
TrbG_Rsp         DVLVGDSVRWKVEPATSGATGGQAIH--------LIVKPSEPGLVTSMVVTTSRRTYHIQ
TrbG_RK2         SINLGDTARWTVEPAITGSGANETQH--------LIIKPMDVGLETSLVVTTDRRSYHMR
TrbG_Eae         SINLGDTARWTVEPAITGSGATEVQH--------LIIKPMDVGLETSLVVITNRRSYHFR
LvhB9_Lpn        DIEGGDTTAWMVTYHPQLENMIFIK-------------PTMFDSKTNMTVITNQRAYYFS
TrbG_Rpr         SISMGDTTSWQIVPAGHRIFIK----------------PMEPDATTNMTLITNKRTYFFE
VirB9_Rpr        NIILGDAYAWKITTLANRLFIK----------------PLEKDIRTNMTIITNKRTYEFD
                                                                         : : 

VirB9_Atu1       ISSKTLPHLDKEQA-----------------------------------DLYYSVQFAYP
VirB9_Atu2       ISSKTLSHLDKEQP-----------------------------------DLYYSVQFAYP
VirB9_Ret        ISSSTLAHLDKEQP-----------------------------------DLYYSVQFAYP
VirB9_Bhe        LQVREGDVSAGN-------------------------------------DTYFLVKFRYP
TrwF_Eco         LQMR-----NDRNG------------------------------------AMYELAFRYP
TraO_Eco         LHFIGEETKKNADGTVSKSFIE---------------------TPWAVRHAVLQLTYEYP
VirB9_Bsu        LRLMP----GRNNQ-----------------------------------RVAYRVQFRYP
VirB9_Bpe        LVLAS----ADAATP--QAL--------------------------QRSRMAYRLQFRYP
ComB2_Hpy1       VFSTTFTSSKHPNLQVFIE-----------------------------DKNYYTNAFIKP
ComB2_Hpy2       VFSTTFTSSKHPNLQVFIE-----------------------------DKNYYSNAFLKP
Cag8_Hpy1        LRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQKELIKQENLNTTAYINR
CagJ99_Hpy2      LRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINR
TrbG_Atu         LKSHA----------------------------------N---------QYMARVGFEYP
TrbG_Atu2        LKSHP----------------------------------T---------QYMARVGFEYP
TrbG_Rsp         LKSHP----------------------------------S---------QYMARVGFEYP
TrbG_RK2         LRSHR----------------------------------T---------QYMPQVSFTYP
TrbG_Eae         LRSHR----------------------------------T---------EYMPQVSFTYP
LvhB9_Lpn        LTSAKKLEQEPG-------------------------------------KKTYALKFEYP
TrbG_Rpr         LYAAETLDIRDP-------------------------------------EMVFNVKFLYP
VirB9_Rpr        IASTELMIGHER-------------------------------------DLVYVIKFYYP
                 :                                                       :   

VirB9_Atu1       ADDAAAPQKAAQEKAVADRIRAEAQYQQRAEGLLEQPATTVGAEDKNWHYVAQGD---RS
VirB9_Atu2       ADDAAARRREAQQRAVVDRLHAEAQYQRKAEDLLDQPVTALGATDSNWHYVAQGD---RS
VirB9_Ret        ADEAAARRKEAQDKAAADRLRGEAQYQRRAADLLDQPATTGATGDRNWHYVAQGD---RS
VirB9_Bhe        EDEALRKKLAEAAKAAQ----------REENFVNDIFNTHEDFGPRNWAYEAQGS---PL
TrwF_Eco         DTQARQTREANARAAVEAA-----------------FEQRVGA-YYNLKYMMSGD---KD
TraO_Eco         FEQQEKAKSAADKKRITQK-----------------LKQTAFAGAKNYQYVMSEQPEMRS
VirB9_Bsu        AAAAAAAVAAAQKRVVQAR-----------------MNARPSP--VNWNYTMQVGTNSAS
VirB9_Bpe        AAPQAASRASPVGPAVPA-----------------------GA--LNRRYAMQVGNGSDG
ComB2_Hpy1       QKENQENMSENAPKDAQKN-------------NKPLKEEKEETKEKEEETIIIGDN--TN
ComB2_Hpy2       Q--NKENVLENALENTPTN-------------NKPLKEKKEETKEKEEETITIGDN--TN
Cag8_Hpy1        VMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKH
CagJ99_Hpy2      VMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKH
TrbG_Atu         EDVSTRLADINARMEAS-----------------TIPGAGVPAEQLNFSYSVSGS---AG
TrbG_Atu2        EDVSTKLADVNARLEAS-----------------TIPGTGVPAEQLSFSYSISGS---AG
TrbG_Rsp         EDVSTKLADINSRLETG-----------------GIPGT--APDKLNFSYSVSGS---AP
TrbG_RK2         EDALAKWDAIKNREQRDRV-------------EKTIPQTGEYLGNLSFNYSVSGS---TS
TrbG_Eae         EEAQAKWDAIQRREKQERT-------------DNTLPVTGEYLGDLSFDYELSGS---AS
LvhB9_Lpn        QPQPVNTKNTTPNKTVH-------------------------PKVVNTAYRFSGS---PQ
TrbG_Rpr         DDENDNMSGHMQTFSTS-----------------LASPDLTHPEKYNFNYYISGS---EE
VirB9_Rpr        K--------------------------------------------KNSNYMARF------
                                                               .             

VirB9_Atu1       LLPLEVFDDGFTTVFHFP---GNVRIPSIYTINPDGK------EAVANYSVKGSY-----
VirB9_Atu2       LLPLEVFDNGFTTVFHFP---GNVRIPSIYTINPDGK------EAVANYSVKGSD-----
VirB9_Ret        LLPLEVFDNGFTTVFRFP---GNVRIPSIYTIDPDGK------EAVANYSVKGSY-----
VirB9_Bhe        IEPASVYDNGKTTTFTFL---GNTEIPAIYLVSLDGQ------EALVPKTIKGNK-----
TrwF_Eco         IAPVNAWDDGRFTYFKFS---ANADLPSIYFVDAEGN------ESLVPRTTVGSSNNI--
TraO_Eco         IQPVHVWDNYRFTRFEFP---ANAELPQVYMISASGK------ETLPNSHVVGENRNI--
VirB9_Bsu        IAPTLAYDDGRFTYLRFP---NNRDFPAAFLVAEDKS------ESIVNSHIDPSAPDI--
VirB9_Bpe        IAPIAAYDDGRHTWLTFR---PGQPFPAVFAVAPDGT------ETLVNLHID-NQS----
ComB2_Hpy1       AMKIIKKDIQKGYKALKS---SQRKWYCLWACSKKSK------LSLMPKEIFNDKQ----
ComB2_Hpy2       AMKIVKKDIQKGYKALKS---SQRKWYCLGICSKKSK------LSLMPKEIFNDKQ----
Cag8_Hpy1        IMPSEIFDDGTFTYFGFK---NITLQPAIFVVQPDGK------LSMTDAAIDPNMTNSGL
CagJ99_Hpy2      IMPSEIFDDGTFTYFGFK---NITLQPAIFVVQPDGK------LSMTDAAIDPNMTNSGL
TrbG_Atu         WRPTRVYSDGEKTYVQFPRSISGQDAPVLFVVS--GG-----QNRIVNYRMKGDM-----
TrbG_Atu2        WRPTRVYSDGLKTYIQFPRSISGQDAPVLFVVS--GG-----QNRIVNYRMKSNM-----
TrbG_Rsp         WKPKRVYSDGAKTYVQFSKSISGQDAPVLFVVS--GG-----QNRIVNYRMNNDM-----
TrbG_RK2         WKPVRVYNDGKKTIIQMPHSMEQTEAPTLLVVRREGGLFSDDETVMVNYRVQGDR-----
TrbG_Eae         WKPVRVYNDGRKTIIEMPGTMQQTEAPTLLVVRKEGGLFTDDETVLVNYRVQGNR-----
LvhB9_Lpn        LVPRHVFDDGKFTYFELS---AQGSVPAIFAVDDQSG-----KESTVNTRREGKF-----
TrbG_Rpr         IAPIKIFDDGEFTYLQFRD--KNAEISGIFAVDDSLR------ESLVNYRLAQDNPN---
VirB9_Rpr        ------------------------------------------------------------
                                                                             

VirB9_Atu1       --VEISSVSRGWRLRDGHTVLCIWNTAY--DPVGRRPE---TGTVRPDVKRVLKEVRG--
VirB9_Atu2       --VEISSVSRGWRLRDGHTVLCIWNAAY--DPVGQRPQ---TGTVRPDVKRVLKGAKG--
VirB9_Ret        --VEISSVSSGWRLRDGNTVLCVWNTAY--DPVGRRPD---TGTVRPDVKRVLMEERG--
VirB9_Bhe        --VIVHATAAQFTLRRGNDVLCIFNKRF--VPAGVNPE---TGTTSPSVQRKVNIGNGYE
TrwF_Eco         --IAVHKVNPKWMIRLGNRALAIFNEAY--DPNGVPND---TGTASPAVRRVNKGGN---
TraO_Eco         --IEVETVAKEWRIRLGDKVVGVRNNNF--APGRGAVA---TGTASPDVRRVQIGEDN--
VirB9_Bsu        --LVLHRVAKQMVLRLGNKVIGIYNESF--NPDGVPAR---DGTTVPGVKRVIKSPGENL
VirB9_Bpe        --LVIHRVAPVLMLRSGASVIRIVNQNG--DASESPAF---ECHAEPAL-----------
ComB2_Hpy1       --FTYFKFDKRLALSKFPVIYKVVDGYD--NPVNTRIVGDYIIAEDVSTKWTLRLGKDYL
ComB2_Hpy2       --FTYFKFDKRLALSKFPVIYKVVDGYD--NPVNTRIVGDYIIAEDVSTKWTLRLGKDYL
Cag8_Hpy1        RWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK--
CagJ99_Hpy2      RWYRVNEIAEKFKLIKDKALVTVIN-GYGKNPLTKNYNIKNYGELERVIKKLPLVRDK--
TrbG_Atu         --MVVDYNVDRAVLVSG---------------VGWKQE-------KVTIRRGGR------
TrbG_Atu2        --MVVDYNIDRAVLVSG---------------VGWKQQ-------KVTISRGGR------
TrbG_Rsp         --MIVDYAVDKAILVSG---------------VGWRQQ-------KITIRRGG-------
TrbG_RK2         --YIVDTIFDKAILIAG---------------VGSSQD-------RVTISRGN-------
TrbG_Eae         --YIVDTVFDRAILIAG---------------VGSSQD-------RVTISRRK-------
LvhB9_Lpn        --IVVQRLAPQFTLRQG----------------GLTAS----VFNTPEINRIRANRRPK-
TrbG_Rpr         -MIILEQVFPKLAIRKGKK-------------VTCVFN--------HSFKAY--------
VirB9_Rpr        ------------------------------------------------------------
                                                                             

VirB9_Atu1       -----------
VirB9_Atu2       -----------
VirB9_Ret        -----------
VirB9_Bhe        -----------
TrwF_Eco         -----------
TraO_Eco         -----------
VirB9_Bsu        Q----------
VirB9_Bpe        -----------
ComB2_Hpy1       CIRFVKRRKGE
ComB2_Hpy2       CIRFVKKGKDE
Cag8_Hpy1        -----------
CagJ99_Hpy2      -----------
TrbG_Atu         -----------
TrbG_Atu2        -----------
TrbG_Rsp         -----------
TrbG_RK2         -----------
TrbG_Eae         -----------
LvhB9_Lpn        -----------
TrbG_Rpr         -----------
VirB9_Rpr        -----------