Dme             ----------MARNVLESSLLGAGFSIIFQILCRILTFGINAYIVRHVGREVLGIMNVRL
Aga             ----------MGRNVLVSSLQNASFSIVFQIICRCITFAINAFIVRNVGREVLGITNVRL
Hsa             ---------MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRL
Kla             --------MNVKNEHMNKFANGVLFLMLGQTLSKGVNFLLNTLLVRYLSPRIFGIT-SFL
Sce             MAKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLLIRFLSPRIFGIT-AFL
Spo             --------MDKSDSLLQSSSKGLRSSIFFQGSSRILTFFLNQLTIRLTSPSAYAFSSIHF
Ath             ------------------------------------------------------------
Cel             ----------------MSLFSSLVHNVRGQLIARIISFAINMYLLRRINNDVLGLVNVRL
                                                                            

Dme             LLLESTLLFLSREAINRAALSANA---------------QQGDRCSWAQLINQMWLTVPI
Aga             LLLESTLLFLSKEAIIRSALSS-----------------RHNKQCSWAQLINQLWITVPV
Hsa             TLLYSTTLFLAREAFRRACLSG-------------------GTQRDWSQTLNLLWLTVPL
Kla             EFLLSTVLFFSRESIRISTLRIKS-----TTDSGKLEKVEDGEDTRTLQSLINFGYIPFV
Sce             EFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHYKSKVLQTAVNFAYIPFW
Spo             EILQSTILFLSRESVRLAMQRIPS------ENAIITSTSTESNKSKKLSDQLQLIKNTSL
Ath             --------------MQFALIPDGP-----------------ESEENVTRILKVAWVTVPL
Cel             TLLYSSILFLTREPLRKAEIIRG----------------------SLPKFINLLWLSPII
                              .  :                                          

Dme             CAVLCAPCLYIWLNWLSAVDAIYASQYEFACYAVAFSCVLELMAESAVFVAQVFCFVKLK
Aga             CFALTLPCLYIWLNWLSAVDAIYAEQYRFGCFAIAFSCIIEMTAEAPIFVGQVFCFVKLK
Hsa             GVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLK
Kla             IGLPLSIILISWQYSNLNSYFIDLPYFKASIFLIWLSILIELVSEPFYLVHQYLLNHFIR
Sce             IGFPLSIGLIAWQYRNINAYFITLPFFRWSIFLIWLSIIVELLSEPFFIVNQFMLNYAAR
Spo             ISVYIGIVISLLVSLFYFYSLPNFPYSKTCIFIYTVSSFIELLSEPYYEVLQWRQKFSKT
Ath             GIAITIAACIFVLWWQNLS---YSDPYAQAIWIHGFACVLELMAEPLYILSQTLLKLQLR
Cel             STVISVVCVYLWYAFSSTSDEVSWSVLLSFPISAIIESIAEPFSVISLRLESKCGSLAQH
                                                   .  . *  .     : .        

Dme             ILLNTLHILVRSAIFLWIVTGD-----------------RSAAINAFAIAQLSSAVTIVL
Aga             VILDTGHIFIRSFIFILIVLIN-----------------KDITIYAFGIAQITSACTIIV
Hsa             VIAESLSVILKSVLTAFLVLWL-----------------PHWGLYIFSLAQLFYTTVLVL
Kla             SKYESLGVTFACVANFIIVVWFEKMVNGVGLELHDDYKQEGIAIFAFAVGKLVHAMTLLA
Sce             SRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDK-EGIAILAFALGKLAHSITLLA
Spo             ASAEGLGTIICSLLSFAISVLGRN---------------KAPSSLPFALGNLSEKVTIFF
Ath             LIVETVATLARCVTLYSLLVMQTN----------------MEKVIIFALSQVAYGGSLFI
Cel             FAIGQGMLICVKRIFVLAGLFMFPG---------------MYHLELFAYAQYIGAIAYLL
                                                              *. .:       . 

Dme             GQYGFFYFYLKGF-KDFVTQQAKKKP-VAPKAWQVSLYEHMDDFPFKQLSDFLPGVMFNP
Aga             GNYAFYYFYIPKL-LQYRKDLKKVDDKYVLRDQYGQHFENMDDFPFVSIKQMLPGVLPNP
Hsa             CYVIYFTKLLG---SPESTKLQT--------------------LPVSRITDLLPNITRN-
Kla             CYSYNYYSEVYTTGERYSYKLTKIRP---------------------ETRQ---------
Sce             CYYWDYLKNFKPK-KLFSTRLTKIKT---------------------RENNELKKGYPKS
Spo             TLRYFAKQPFS----IFLHKVGE-----------------------------------NE
Ath             GYWAYFLICGVYR----SSNLFPFRP---------------------------------G
Cel             FNFVAFYIYIRNKSIPELEQFSTFS------------------------------DLFPK
                                                                            

Dme             NGKHFNRELQTLTLSFVKQGVLKQILTEGEKYVMSVSPVLSFGEQATYDVVNNLGSMAAR
Aga             NS-MFNSDLQTLVLSFAKQGVLKQVLTEGEKYVMSVSPVLTFSEQATYDVVNNMGSLAAR
Hsa             -GAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVAR
Kla             ESYYFQNDTVQHFKKVYFQLCFKHLLTEGDKLIINS--LCTVEEQGIYSLLSNYGSLITR
Sce             TSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIINS--LCTVEEQGIYALLSNYGSLLTR
Spo             RYIFWDSSTLRIICSHTYQVLLKHLITKGDKIMVAWY--ASPSAQGPYALASNYGSLLAR
Ath             NFMDFDNDLSKMCKLFTFQSFRKLILQ------------------EVLKTP---GSLVVR
Cel             FSEGIDRDSIHAVFTMFSHSILKQLLTDGSAYVMTFTELLSLKDQAVYDAVERVGSIIVR
                     : .          :   * ::                            **: .*

Dme             FIFRPIEDSSYFYFTQTLSRDIKLAKQPQERVRQASSVLNNLLLGVSSIGLIAFTFGQSY
Aga             FIFRPIEDSSYFYFTQTIARDSALAEQKREMVQEASDVLAYVMKTVTSIGLLAFVFAQSY
Hsa             LIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAY
Kla             LLFAPIEEALRLFLAALLR------LCCKKNLWLSMKVLIDLTKFYLYLSLFIIIFGPIN
Sce             LLFAPIEESLRLFLARLLS------SHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPAN
Spo             IVFRPVEDHSHIVFAQLTHYK------NKKDEKKALNLLAWILKLYSYMSLFILFG-SNY
Ath             MVFLPFEESSYTIFARFASG------DYQERNKKLGIYLTVALKLVILIGLIFMAFGPSY
Cel             TILSPIDENCNAYFSNTIRKESSVFNKNTDNHDDLVDTLSKVLHVVGVIGFVACTFGIPY
                 :: *.::     ::              .        *          .:         

Dme             SYPVLLLYGGPDFVAGGLPQSLLQWHCLAIYLLAVNGISEGYMFATNTSRDIDKYNYLMA
Aga             SGTVLLLYGGADFVEGGLPEQLLRWHSLAIVLLAPNGITEGYMFATNTSKQIDTYNYYMA
Hsa             SQLALDIYGG-TMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVML
Kla             SSYLLKFVIG-SKWSSTSFLETIRTYCFYIPFLSLNGIFEAFFQSVAPVI----------
Sce             SSFLLQFLIG-SKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMM
Spo             SDIVLLFGAG-SKWASPDSSSILSWYAMYIPFMAANGVLEAFYVSAANSSQLYDQGKCYL
Ath             SYSLIRLLYG-EKWSDGEASLALQFYCLYIIVLAMNGTSEAFLHAVGTKNELERSNDMLL
Cel             SPVVISLYGG-KLLSENGGALLLSLYSGYILVTAINGITEGFAMASMDNRQIFTHGKFLF
                *   : :  *            :  :.  : . : **  * :  :               

Dme             IFSVSFLVLSYILTG--IFGPVGFIFANCINMLSRILYSTYYIRHQYRPLSLDPLLGLWP
Aga             FFSVTFLLLSYQLTN--WFGPVGFILANCCNMSFRISYSVFYITKHFRSIGMNPLQKSLP
Hsa             ALSSSFLVLSYLLTR--WCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHL
Kla             ------------------------------------------------------------
Sce             AFSGIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRELFTDSSFFFNF
Spo             ASAVFYFITGKFLLSWFNLGSHGLILANILNLSLRICFALRFILHNYKDFSLPRSLPRPF
Ath             IFSLIYVALNILLIR--SAGAIGLIMANSLSWQILILSSIITLISEKTILDRKNFWETFP
Cel             VTSIIHLIINYVLCVY--MNSAGFIVANIINMSVRIIYNWRTIREYLGDKCPSFTEVLPT
                                                                            

Dme             GKLFGCTLFLAGIVCYWYQSSD--------LATHLGVGVLAGLACLLSWALAHRDLVRLA
Aga             GPMYLSVLIVSGIVCKVSEAYFSGRS----IVCHLLVGVLCTGLSVGTWSFENRDLLR--
Hsa             SPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFL
Kla             ------------------------------------------------------------
Sce             KDFKTVIIAGSTICLLDWWFIGYVKN-----LQQFVVNVLFAMGLLALILVKERQTIQSF
Spo             LLALSILLSIISSFLVKHWRESKVP-----FLVYFLSAPSLAILYSCFIILVDKDVRGYA
Ath             --------------------------------LHFGIGVICFCLSAIVIYRRERVFIKRI
Cel             G-QTSIFLGVSLLATSFTYLLFATTPGLSYTLAHIAIGAVCLILTAQDTAQHDSVFTVIV
                                                                            

Dme             WRYGRRIKIE----
Aga             --------------
Hsa             RTQLGVPRRTDKMT
Kla             --------------
Sce             INKRAVSNSKDV--
Spo             KILLSKYYIK----
Ath             KRFRDYNHDD----
Cel             DSLAKKHRD-----